Comparison tool
Compare peptides
Pick up to three compounds. Useful for deciding whether two peptides in a stack actually do different things, or whether you're paying twice for the same pathway.
Select up to three (1/3)
Comparison results
| Attribute | |
|---|---|
| Category | Metabolic |
| Evidence grade | Emerging |
| Also known as | Mitochondrial open reading frame of the 12S rRNA-c, MT-RNR1-encoded peptide |
| Mechanism | Encoded by mitochondrial 12S rRNA, MOTS-c translocates to the nucleus and activates the folate/AMPK axis. This improves cellular glucose uptake, increases fatty-acid oxidation and promotes metabolic flexibility under nutrient stress. |
| Key benefits | Improved insulin sensitivity and glucose disposal in rodent models · Enhanced fat oxidation and reduced fat accumulation · Exercise-mimetic effects on metabolism and physical capacity · Potential protection against diet-induced metabolic dysfunction |
| Side effects | Limited human safety data · Injection-site irritation · Possible hypoglycaemia in susceptible individuals |
| Half-life | Estimated minutes to a few hours |
| Administration | Subcutaneous injection; oral capsules are marketed but less validated |
| Dosing overview | Commonly cited at 5–10 mg daily, often for 4–12 week cycles |
| Storage | Lyophilised powder refrigerated; reconstituted vials 2–8 °C and used within ~30 days |
| Legal status | Research chemical; not approved as a drug. |
Dosing figures reflect published literature and commonly reported community protocols. They are informational only.
Head-to-head comparisons
Each comparison below is its own page with the full attribute table, key differences and shared attributes for that pairing. They are grouped by the category the compounds are indexed under.
GLP-1 receptor agonists
Direct comparisons between the incretin-based compounds most often searched against one another.
Metabolic and GLP-1 compounds
Compounds indexed under metabolic use, including the GLP-1 receptor agonists and the smaller fat-metabolism peptides often searched alongside them.
Recovery and tissue repair
Pairings between compounds indexed for healing, connective tissue and post-injury recovery.
Growth-hormone axis
Secretagogues and releasing peptides that act on growth-hormone signalling, compared with each other and with adjacent compounds.
Longevity and mitochondrial
Compounds indexed under longevity, cellular and mitochondrial function.
Sexual health
Melanocortin and related compounds indexed for sexual-health use.