Comparison tool
Compare peptides
Pick up to three compounds. Useful for deciding whether two peptides in a stack actually do different things, or whether you're paying twice for the same pathway.
Select up to three (1/3)
Comparison results
| Attribute | |
|---|---|
| Category | Sexual health |
| Evidence grade | Strong |
| Also known as | Bremelanotide, Vyleesi |
| Mechanism | Selectively activates MC4R in the hypothalamus, increasing dopaminergic signalling in the medial preoptic area — driving desire itself rather than blood flow, unlike PDE5 inhibitors. |
| Key benefits | Increased sexual desire in both sexes · Works independently of vascular function · Effective as an on-demand dose |
| Side effects | Nausea and vomiting · Flushing · Headache · Transient blood-pressure increase |
| Half-life | About 2.7 hours |
| Administration | Subcutaneous auto-injector, 45 minutes before activity |
| Dosing overview | 1.75 mg as needed, maximum one dose per 24 hours |
| Storage | Room temperature for the approved auto-injector |
| Legal status | FDA-approved (Vyleesi) for premenopausal HSDD; other uses are off-label. |
Dosing figures reflect published literature and commonly reported community protocols. They are informational only.
Head-to-head comparisons
Each comparison below is its own page with the full attribute table, key differences and shared attributes for that pairing. They are grouped by the category the compounds are indexed under.
GLP-1 receptor agonists
Direct comparisons between the incretin-based compounds most often searched against one another.
Metabolic and GLP-1 compounds
Compounds indexed under metabolic use, including the GLP-1 receptor agonists and the smaller fat-metabolism peptides often searched alongside them.
Recovery and tissue repair
Pairings between compounds indexed for healing, connective tissue and post-injury recovery.
Growth-hormone axis
Secretagogues and releasing peptides that act on growth-hormone signalling, compared with each other and with adjacent compounds.
Longevity and mitochondrial
Compounds indexed under longevity, cellular and mitochondrial function.
Sexual health
Melanocortin and related compounds indexed for sexual-health use.