Comparison tool
Compare peptides
Pick up to three compounds. Useful for deciding whether two peptides in a stack actually do different things, or whether you're paying twice for the same pathway.
Select up to three (1/3)
Comparison results
| Attribute | |
|---|---|
| Category | Metabolic |
| Evidence grade | Strong |
| Also known as | LY3437943, Triple G |
| Mechanism | Simultaneously activates GLP-1, GIP and glucagon receptors in a single peptide. The glucagon component increases energy expenditure and hepatic lipid oxidation, while GLP-1 and GIP suppress appetite, slow gastric emptying and improve glucose-dependent insulin secretion. |
| Key benefits | Up to ~24% mean weight loss at 12 mg over 48 weeks in phase 2 · Large reductions in HbA1c and liver fat · Improvements in blood pressure, triglycerides and LDL cholesterol |
| Side effects | Nausea and vomiting · Diarrhoea · Gallbladder issues · Mild resting heart-rate increase · Injection-site reaction |
| Half-life | About 5–7 days |
| Administration | Once-weekly subcutaneous injection |
| Dosing overview | Phase 2 started at 2 mg weekly and escalated to 12 mg over several weeks |
| Storage | Investigational product; typically refrigerated as lyophilised or pen formulation |
| Legal status | Investigational drug; not FDA-approved as of 2026. |
Dosing figures reflect published literature and commonly reported community protocols. They are informational only.
Head-to-head comparisons
Each comparison below is its own page with the full attribute table, key differences and shared attributes for that pairing. They are grouped by the category the compounds are indexed under.
GLP-1 receptor agonists
Direct comparisons between the incretin-based compounds most often searched against one another.
Metabolic and GLP-1 compounds
Compounds indexed under metabolic use, including the GLP-1 receptor agonists and the smaller fat-metabolism peptides often searched alongside them.
Recovery and tissue repair
Pairings between compounds indexed for healing, connective tissue and post-injury recovery.
Growth-hormone axis
Secretagogues and releasing peptides that act on growth-hormone signalling, compared with each other and with adjacent compounds.
Longevity and mitochondrial
Compounds indexed under longevity, cellular and mitochondrial function.
Sexual health
Melanocortin and related compounds indexed for sexual-health use.